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Christopher R Chapple Selected Research

Prostatic Hyperplasia (Benign Prostatic Hyperplasia)

1/2017Prostatic urethral lift vs transurethral resection of the prostate: 2-year results of the BPH6 prospective, multicentre, randomized study.
10/2015Prospective, randomized, multinational study of prostatic urethral lift versus transurethral resection of the prostate: 12-month results from the BPH6 study.
5/2015Individual patient data from registrational trials of silodosin in the treatment of non-neurogenic male lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH): subgroup analyses of efficacy and safety data.
9/2014A pooled analysis of individual patient data from registrational trials of silodosin in the treatment of non-neurogenic male lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH).
4/2014Non-Hormonal treatment of BPH/BOO.
10/2012Silodosin : a new subtype selective alpha-1 antagonist for the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.
3/2011Silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: results of an international, randomized, double-blind, placebo- and active-controlled clinical trial performed in Europe.
3/2007Durability and cost-effectiveness of transurethral needle ablation of the prostate as an alternative to transurethral resection of the prostate when alpha-adrenergic antagonist therapy fails.
9/2004Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician.
1/2004A rational approach to benign prostatic hyperplasia evaluation: recent advances.

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Christopher R Chapple Research Topics

Disease

45Overactive Urinary Bladder (Overactive Bladder)
01/2022 - 01/2002
16Stress Urinary Incontinence
02/2024 - 07/2003
16Lower Urinary Tract Symptoms
01/2017 - 09/2004
10Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2017 - 01/2004
7Urinary Incontinence
01/2019 - 07/2006
6Pain (Aches)
09/2021 - 02/2007
5Nocturia
10/2017 - 11/2004
4Pathologic Constriction (Stenosis)
10/2023 - 09/2008
4Prostatic Neoplasms (Prostate Cancer)
12/2021 - 08/2008
4Urinary Tract Infections (Urinary Tract Infection)
10/2021 - 01/2014
4Urethral Stricture
01/2021 - 04/2015
4Pelvic Organ Prolapse
01/2020 - 01/2012
4Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
12/2019 - 04/2006
4Constipation
10/2017 - 11/2002
4Urinary Retention
10/2017 - 02/2005
3Dizziness (Lightheadedness)
05/2015 - 08/2013
3Orthostatic Hypotension (Postural Hypotension)
05/2015 - 01/2005
3Urge Urinary Incontinence (Urge Incontinence)
07/2005 - 11/2002
2Interstitial Cystitis (Interstitial Cystitis, Chronic)
07/2021 - 10/2007
2Inflammation (Inflammations)
01/2020 - 10/2013
2Retrograde Ejaculation
12/2019 - 05/2015
2Neoplasms (Cancer)
08/2019 - 01/2019
2Spinal Cord Injuries (Spinal Cord Injury)
03/2019 - 11/2002
2Hypertension (High Blood Pressure)
05/2017 - 01/2014
2Tachycardia (Tachyarrhythmias)
05/2017 - 11/2002
1Cysts
01/2023
1Diverticulum
01/2023
1Underactive Urinary Bladder
01/2022
1Hemorrhage
10/2021
1Pruritus (Itching)
10/2021
1Asymptomatic Infections
01/2020
1Spasm (Spasms)
01/2020
1Edema (Dropsy)
12/2019
1Congenital Abnormalities (Deformity)
09/2019
1Fatigue
01/2019
1Sexually Transmitted Diseases (Sexually Transmitted Disease)
01/2019
1Sneezing
01/2019
1Dyspepsia (Indigestion)
10/2017
1Fistula
01/2016

Drug/Important Bio-Agent (IBA)

17Muscarinic AntagonistsIBA
01/2020 - 11/2002
15mirabegronIBA
01/2020 - 02/2013
9Solifenacin SuccinateFDA Link
01/2019 - 01/2005
5Botulinum Toxins (Botulinum Toxin)IBA
01/2020 - 07/2006
5silodosinFDA Link
05/2015 - 03/2011
5Tolterodine Tartrate (Detrol)FDA Link
11/2010 - 01/2002
4Prostate-Specific Antigen (Semenogelase)IBA
12/2021 - 01/2004
4Cholinergic Agents (Cholinergics)IBA
04/2014 - 11/2004
3Polypropylenes (Polypropylene)IBA
02/2024 - 01/2019
3Adrenergic Receptors (Adrenergic Receptor)IBA
06/2018 - 04/2014
3Cholinergic Antagonists (Anticholinergics)IBA
11/2017 - 11/2002
3Type A Botulinum Toxins (Botox)FDA Link
11/2017 - 08/2013
3Tamsulosin (Flomax)FDA LinkGeneric
03/2011 - 01/2005
3Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
08/2008 - 11/2002
2Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 07/2014
2oxybutynin (Tavor)FDA LinkGeneric
07/2009 - 01/2002
2Adenosine Triphosphate (ATP)IBA
10/2007 - 10/2002
2darifenacinFDA Link
11/2004 - 11/2002
1BulkamidIBA
01/2023
1Contrast MediaIBA
01/2023
1Muscarinic M3 ReceptorIBA
01/2022
1SteroidsIBA
10/2021
1Captopril (Capoten)FDA LinkGeneric
10/2021
1TamoxifenFDA LinkGeneric
10/2021
1A-factor (Streptomyces)IBA
01/2020
1HolmiumIBA
12/2019
1potassium titanylphosphateIBA
12/2019
1Mineral Oil (Liquid Paraffin)FDA LinkGeneric
09/2019
1Biomarkers (Surrogate Marker)IBA
08/2019
1Estradiol (Delestrogen)FDA LinkGeneric
01/2019
1Biocompatible Materials (Biomaterials)IBA
01/2019
1HydrogelsIBA
01/2019
1Mitomycin (Mitomycin-C)FDA LinkGeneric
12/2018
1CollagenIBA
04/2018
1N- (4- ((5- (hydroxy(phenyl)methyl)pyrrolidin- 2- yl)methyl)phenyl)- 4- oxo- 4,6,7,8- tetrahydropyrrolo(1,2- a)pyrimidine- 6- carboxamideIBA
01/2018
1Dihydrotachysterol (AT 10)IBA
01/2017
1Phosphodiesterase InhibitorsIBA
08/2016
1Midazolam (Versed)FDA LinkGeneric
01/2016

Therapy/Procedure

28Therapeutics
01/2021 - 11/2002
10Drug Therapy (Chemotherapy)
01/2022 - 01/2004
5Suburethral Slings (Tension-Free Vaginal Tape)
10/2017 - 07/2003
4Cystectomy
09/2021 - 03/2006
3Injections
01/2023 - 08/2008
2Catheters
01/2020 - 02/2005
2Transurethral Resection of Prostate (TURP)
12/2019 - 10/2015
1Operative Time
10/2023
1Bathroom Equipment
01/2020
1Surgical Mesh
01/2020
1Aftercare (After-Treatment)
01/2020
1Indwelling Catheters (Indwelling Catheter)
01/2020
1Solid-State Lasers
12/2019
1Electrocoagulation (Electrocautery)
12/2019
1Semiconductor Lasers
12/2019
1Combined Modality Therapy
08/2019
1Transplantation
03/2019
1Laminectomy
03/2019
1Radiotherapy
01/2019
1Bioreactors (Bioreactor)
01/2019
1Massage (Zone Therapy)
07/2015
1Sutures (Suture)
04/2015
1Transcutaneous Electric Nerve Stimulation (TENS)
04/2015